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OCR: Additionally, extracellular fluid volum na flow all glomerular filtration rate and renal pla ent. In increase substantially with GH replacen essive and adults with GH deficiency, body fat is e; al) than is distributed in a more central (abdom t, body fat peripheral pattern. With GH replaceme lean body decreases in parallel with the increase i rst month mass; a mean 5kg loss of body fat in the orted, and of GH replacement therapy has been rej tral' sites this loss is particularly marked from 'ce (Fig. 2.30).